Practical issues for developing your AEFI investigation procedures

  • Decide what should be investigated (develop the reporting system around these events), based on case definitions and identification of AEFI clusters (see below for cluster investigation).
  • Decide who should conduct investigations and in what timeframe.
  • Design the investigation procedure and forms to collect all relevant information for determining cause and assessing causality.
  • Have a system in place for collecting and testing any samples of suspect vaccines and diluents.
  • Have a system in place to conduct post mortems and test samples from patients (blood samples, etc.)
  • Decide which events require high-level versus lower-level investigation.